Targeted Somatic Profiling with HRD
A 523-gene, NATA-accredited solid-tumour service delivering actionable DNA variants, RNA fusions, MSI, TMB and HRD through a single clinical report.
Performed through AGRF's Australian ISO 15189 clinical laboratory. Turnaround: 15 business days standard, including extraction. Priority processing available.
523
55
genes on the DNA panel
genes assessed for RNA fusions
One sample.
One test.
One clinical report.
15
business days, sample to report
01 DNA variants across 523 genes
Single-nucleotide variants, indels and copy number variants (amplifications and deletions)
02 RNA gene fusions
55-gene fusion subset
03 MSI and TMB
Microsatellite instability and tumour mutational burden
04 Homologous recombination deficiency (HRD)
A genome-wide genomic instability score (GIS) with BRCA1/2 status, identifying HRD beyond BRCA alone
Fewer tests. One sample. One clinical report.
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Consolidated result
One test rather than multiple molecular tests ordered separately. Fewer sequential and reflex tests, tissue preserved.
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NATA-accredited for reporting
Performed in AGRF's ISO 15189 accredited clinical laboratory and reported in-house under our own accreditation.
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Australian sample processing
Samples are not exported offshore.
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Australian data governance
Genomic data held under Australian frameworks.
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Reliable turnaround time
15 business days standard, including extraction. Priority processing available.
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National service, local support
A clinical team in Australia you can pick up the phone to.
Request via our clinical team
Email clinical@agrf.org.au and our clinical team will confirm sample requirements, request forms and delivery details.
523 genes. 55 fusion targets.
DNA coverage for small variants and, for most genes, copy number variants. RNA gene-fusion detection covers the 55-gene subset highlighted in magenta.